The landscape of heroin addiction treatment is constantly evolving, driven by the relentless pursuit of evidence-based treatment modalities, novel therapeutic technologies, and comprehensive patient-centered care models. It is a milieu of innovations driven by the urgency to address the rising cases of heroin addiction that has plagued society for decades. It is evident that the future holds numerous transformations.

As we delve into the future of heroin rehabilitation, it is crucial to note that heroin addiction is a complex disease. Biologically, it disruptively alters the brain's neurochemical structures, leading to physical dependency. Psychologically, it triggers maladaptive behaviors and mental health disorders, while sociologically, it catalyzes a cascade of personal and societal issues. Understanding these multifaceted aspects of heroin addiction is a precursor to dissecting the future trends in heroin rehabilitation.

One of the significant breakthroughs to anticipate is the adoption of precision medicine in addiction treatment. Precision medicine embraces the concept of individuality in disease etiology, progression, and treatment response. It's grounded on the realization that the genetic and epigenetic makeup of an individual significantly influences their vulnerability to addiction and their response to treatment.

Genome-wide association studies (GWAS) have identified multiple risk genes associated with heroin addiction. Understanding the genetic makeup of an individual could assist in predicting their vulnerability to addiction and tailoring personalized treatment plans. This approach could revolutionize the future of heroin rehab by improving treatment outcomes and reducing relapse rates.

Another anticipated trend is the integration of artificial intelligence (AI) and machine learning in addiction treatment. AI, in its multidimensional aspects, could transform the addiction recovery industry by improving diagnosis, prognostication, and therapeutic interventions.

AI-based predictive models could be used to identify individuals at high risk of developing heroin addiction. This approach could enhance early intervention strategies, thus curtailing the progression of the disease. In the treatment panorama, AI could be employed in cognitive behavioral therapy to identify behavioral patterns predictive of relapse and initiate appropriate interventions.

Furthermore, the use of virtual reality (VR) in addiction treatment is an exciting prospect that could revolutionize heroin rehab. VR can be used in exposure therapy, a behavioral therapy technique where addicts are exposed to cues associated with drug use in a controlled virtual environment. This exposure helps them develop coping strategies to combat cravings. The efficacy of VR in addiction treatment has been substantiated in multiple randomized controlled trials, with results indicating significant reductions in craving levels.

Additionally, the notion of comprehensive patient-centered care has gained momentum in recent years. This approach acknowledges the interplay between heroin addiction and comorbid conditions, such as mental health disorders, and emphasizes the need for integrated treatment plans. The benefits of integrated care include improved treatment adherence, reduced relapse rates, and enhanced quality of life.

In conclusion, the future of heroin rehab is gleaming with optimism, anchored on scientific breakthroughs, innovative technologies, and the relentless quest for holistic, patient-centered care. However, we must acknowledge the inherent uncertainties in any prediction. While the current trends hold immense promise, the actualization of these advancements will rely on rigorous clinical trials, development of legal and ethical frameworks, and financial investments. The course of the future remains largely in our hands, determined by the diligence and earnestness of our efforts.